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SCIENTIFIC PATHWAYS IN INFLAMMATION & IMMUNOLOGY

DISCOVER PATHWAYS UNDER INVESTIGATION1

The JAK pathway plays an important role in a number of inflammatory diseases. Select the hexagon to explore more about the JAK pathway.

The TEC pathway plays an important role in regulating the inflammatory response. Inhibiting this pathway may have implications for multiple conditions. Select the hexagon to explore more about the TEC pathway.

IRAK4 plays an important role in innate immunity. Inhibiting IRAK4 kinase activity may have implications for chronic inflammatory diseases. Select the hexagon to explore more about the IRAK4 pathway.

The TNF superfamily member ligand TNFSF15, also known as TL1a, is associated with the expression of proinflammatory cytokines. Select the hexagon to explore more about the TNFSF15 pathway.

IL-10 is an anti-inflammatory cytokine that may help reduce inflammation in multiple diseases. Select the hexagon to explore more about the IL-10 pathway.

ADVANCING RESEARCH WITH THE GOAL OF LIFE-CHANGING IMPACT

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