Scientific Pathways in INFLAMMATION & IMMUNOLOGY

DISCOVER PATHWAYS UNDER INVESTIGATION1

JAK inhibition may be a factor in a number of inflammatory diseases. Select the hexagon to explore more about the JAK pathway.

Inhibition of TEC family of non-receptor tyrosine kinases may have implications for multiple conditions. Select the hexagon to explore more about the TEC pathways.

IRAK4 plays an important role in innate immunity.1 Inhibiting IRAK4 kinase activity may have implications for chronic inflammatory diseases. Select the hexagon to explore more about the IRAK4 pathway.

The TNF superfamily member ligand TNFSF15 is associated with the expression of proinflammatory cytokines. Select the hexagon to explore more about the TNFSF15 pathway.

IL-10 is an anti-inflammatory cytokine that may help reduce inflammation in multiple diseases. Select the hexagon to explore more about the IL-10 pathway.

ADVANCING RESEARCH WITH THE GOAL OF LIFE-CHANGING IMPACT

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